Commensal-driven serotonin production modulates in vivo delivery of synthetic and viral vectors

INTRODUCTIONIn vivo delivery systems (IDSs) are essential for enabling the clinical use of therapeutic agents …

Intestinal interoceptive dysfunction drives age-associated cognitive decline

AbstractAgeing is accompanied by declining memory function, with extremely heterogeneous manifestation in the …

Mucosal vaccination in mice provides protection from diverse respiratory threats

An intranasal liposomal formulation combining toll-like receptor (TLR) 4 and 7/8 ligands with a model antigen,…

Intestinal macrophages modulate synucleinopathy along the gut–brain axis

ME-Macs as early cellular initiators of αS pathology along the gut–brain axis. Understanding these mechanism…

Convergent evolution of scavenger cell development at brain borders

muLECs and BAMs share functional analogies but are not homologous, providing an example of convergent evolutio…