The transition from monocyte to tissue-resident macrophage requires DHPS
A cell-intrinsic, tissue-agnostic pathway that drives differentiation of monocyte-derived macrophages into RTM…
A cell-intrinsic, tissue-agnostic pathway that drives differentiation of monocyte-derived macrophages into RTM…
AbstractObesity is a major disease risk factor due to obesity-associated hyperinflammation. We found that obes…
The indispensable role of ARPC5-containing, but not ARPC5L-containing, Arp2/3 complexes in mononuclear phagocy…
macrophages are key for MR1 antigen presentation and MAIT cell immunity.…
Highlights•MiTEs are novel myeloid-targeted immunocytokine prodrugs for cancer immunotherapy•TREM2 antagonis…
PU.1 expression in microglia is regulated not only genetically but also epigenetically by the microenvironment…
AbstractAll mammalian organs depend on resident macrophage populations to coordinate repair and facilitate tis…
Efferocytosis-associated reprogramming of the islet macrophages and the subsequent influence on the adaptive i…
A targetable epigenetic node of myeloid progenitor dysregulation that sustains immunoregulatory mo-macs in the…
Highlights•Astrocyte processes reduce contact with synapses before synapse removal by microglia•Microglia-de…
Highlights•Erythroblast island (EBI) macrophages are recruited to the bone metastatic niche•EBI macrophages …
In addition to their role in host defense, macrophages contribute to the development and remodeling of tissues…
AbstractAs tissue resident macrophages of the central nervous system (CNS) parenchyma, microglia perform diver…
Macrophages sense deviation in intracellular pH as a mechanism to guide the control of inflammatory responses.…
Healthy tissue may be damaged by the activity of immune cells working to eradicate infection. Hoagland et al. …
AbstractAs tissue resident macrophages of the central nervous system (CNS) parenchyma, microglia perform diver…
